The full article is available in JAIDS (Journal of Acquired Immune Deficiency Syndromes)
Little is known about the evolution of programme outcomes associated with rapid expansion of ART in resource-limited settings. We describe temporal trends and assess associations with mortality and loss to follow-up (LTFU) in HIV cohorts from 8 countries.
Multi-cohort study using electronic health records.
Analysis included adults in twenty-five Médecins Sans Frontières supported programmes initiating ART between 2001 and 2011. Kaplan-Meier methods were used to describe time to death or LTFU, and proportional hazards models to assess associations with individual and programme factors.
As ART expands in resource-limited settings, challenges remain in improving access to ART and preventing programme attrition. There is an urgent need for novel and sustainable models of care to increase long-term retention of patients.
Anna GRIMSRUD, Suna BALKAN, Esther C CASAS, Johnny LUJAN, Gilles VAN CUTSEM, Elisabeth POULET, Landon MYER, Mar PUJADES-RODRIGUEZ.