Linezolid Fact Sheet

Tuberculosis is the leading cause of death in South Africa, and the country has a growing epidemic of drug-resistant tuberculosis (DR-TB). Every year, approximately 15,000 people are diagnosed with multi-drug resistant TB (MDR-TB), with a substantial proportion of these found to have more extensively drug resistant TB (XDR-TB).

MDR-TB is resistant to isoniazid and rifampicin—the two most commonly used anti-TB drugs—while XDR-TB is also resistant to at least half of the second-line medicines used to treat MDR-TB.

Less than half of the patients diagnosed with DR-TB in South Africa are started on treatment. Of those who do start on treatment, only about half of those patients with MDR-TB, and less than 20% of patients with XDR-TB are cured.

Download the fact sheet: Linezolid Fact Sheet